The Mandarin Oriental, Boston
Besides the in-room Playstation 3s, massive Spa by Mandarin and a welcome beverage for travel-weary arriving guests, the Mandarin Oriental is literally attached to the Prudential Center Mall, one of Boston's most popular shopping destinations.
The Westin Copley Place, Boston
It may not be as luxurious as the nearby Mandarin Oriental, but the West Copley Place should not be overlooked by the hardcore Black Friday shopper: It's attached to The Copley Place Shopping Mall via skywalk, home to some of Boston's best high-end shopping, such as Tiffany's, Louis Vuitton, Burberry and Neiman Marcus.
Wynn Las Vegas
Vegas may have invented the hotel as an all-in-one destination, but the Wynn Las Vegas reinvented the shopping aspect of it. The shopping is about high-end as the hotel, though (think Rolex and Oscar de la Renta).
Shoppers who are into gambling at blackjack tables as much as they are into braving Black Friday crowds are probably already aware of the Bellagio's fantastic shopping. Like the Wynn, it's upscale, but anyone spending the day after Thanksgiving in Las Vegas probably wouldn't mind picking up gifts at Prada and Dior.
The Ritz-Carlton Chicago, a Four Seasons Hotel
The Ritz-Carlton Chicago is attached to the Water Tower Place Shopping Mall, which houses all the standard mid-level shops like Macy's, Banana Republic and Swarovski. You can finish up your day of braving the shopping hordes with some treatments at the full service spa or a dip in the Jacuzzi.
The Drake Hotel
Chicago shoppers who are more into historic ambiance than spa pampering should probably opt for the Drake Hotel. Even though there's plenty of amazing shopping in the nearby Gold Coast area, the lobby already houses a shopping arcade with a Chanel store (don't worry: we won't tell if you pick something up for yourself).
Atlantis Paradise Island Resort
If you had the foresight to book a stay in the Bahamas for the Thanksgiving holiday, you already have a leg up on "desirable location." You also have the added advantage of the Atlantis' high-end shops (open to the public), which you can expect to be less crowded than any high-end mall in the United States.