Termini station location is gritty, and a bit far from popular sights
The 197-room Una Hotel is an upscale option near Termini station, a slightly gritty area that's a bit far from popular tourist sights. The rooms are clean and modern, with wooden accents, white and beige decor, and flat-screen TVs. Large slate bathrooms are the highlight, and come with bidets and rainfall showerheads. There is an on-site restaurant and bar as well as a free breakfast. Rates here are often cheaper than at comparable hotels in quainter, more central areas, though it may be worth comparing prices with the Hotel Trevi Collection.
The UNA Hotel is within walking distance of a few attractions and trattorias, and is just a block from Termini station, the main bus and train hub in Rome. This means lots of traffic, but a convenient location for those arriving to the city by train for a short visit.
This area is oftentimes not the "Rome" that people expect upon arriving, meaning it's not super picturesque -- roads here are paved rather than cobblestone. But it has slowly been improving over the last couple of decades, and is home to several centuries-old structures, such as the ruins of the Baths of Diocletian (ancient public baths dating back to 298 AD), the adjacent Basilica di Santa Maria Maggiore, and the Michelangelo-designed Santa Maria degli Angeli.
26-minute drive to Rome Ciampino International Airport
49-minute drive to Leonardo da Vinci-Fiumicino Airport
2-minute walk to the Termini station
4-minute walk to the Basilica di Santa Maria Maggiore
6-minute walk to the Opera House
7-minute walk to the Baths of Diocletian
9-minute walk to the National Art Gallery
9-minute walk to Santa Maria degli Angeli
14-minute walk to Palazzo Barberini
14-minute walk to the Trevi Fountain
20-minute walk, or 6-minute drive, to the Colosseum