Palazzo Resort Hotel Casino Rating: 5.0 Pearls
Styled a little softer and more feminine than the bachelor-swank of rival Wynn, the enormous rooms at the Palazzo could host a small party. But it's what's outside the rooms that makes this our top pick: The Tao and Lavo nightclubs are among the hippest party scenes on the Strip). The hotel's world-famous Canyon Ranch Spa is arguably the best spa in town. The hotel houses some of the Strip's best restaurants, including the Japanese-Peruvian-Brazilian cuisine of SushiSamba. And the shops at the Palazzo include top names like Tory Burch and Diane von Furstenberg, plus an 85,000-square-foot Barneys New York.
Bellagio Rating: 5.0 Pearls
Designed to look like an enormous Italian villa, Bellagio offers serenity (it even has its own botanical gardens) as well as a prime central location for hitting parties on or off the Strip (virtually all the notable clubs are just a short cab ride away). Pamper the whole party at the spa's whirlpools, eucalyptus steam room, and sauna. The group can also enjoy spa manicures and pedicures together while sipping champagne in a private room. Pick from one of the hotel's 20-plus restaurants for dinner. Later, burn off the booze and food with a Pilates, cardio, or body-sculpting class at the excellent fitness center.
Rio All Suites Hotel & Casino Rating: 3.5 Pearls
The wallet-friendly standard rooms at the Rio are oversize suites that sleep five -- perfect for a group in search of bargain accommodations. A bachelorette and her friends may also appreciate the Rio Spa & Salon's "Sip and Spa" package. Start with a free drink at the lobby lounge, then choose from four discounted treatments at the spa, and end with 2-for-1 drink coupons and free access to the popular rooftop lounge. For far more party options, squeeze into a cab for a quick ride to the Palms down the street.
The Palms Casino Resort Rating: 4.0 Pearls
If what the bride-to-be needs is to feel sexy, head to the Palms' coed hammam (Turkish bath) at the chic Drift Spa. When night falls, hit the hotel's popular Rain nightclub or Moon, another club with live DJs, multiple bars, and a retractable roof. For an especially girly getaway, consider the 2,350-square-foot Barbie Suite, decorated with framed Barbie prints, a fireplace, super-pink Barbie patterns on the pillows and walls, and 65 Barbie dolls mounted on a mirror.
Wynn Las Vegas Rating: 5.0 Pearls
Luxury pick Wynn is home to Tryst, one of Vegas' swankiest nightclubs. Getting beyond the bouncer can be tough, but a group of women should fare well (short skirts might help). The hotel's more intimate nightclub, Blush, has outdoor seating. Beyond the clubs, the gorgeous spa, and the classy "European pool" (where you can sunbathe topless), the biggest perk at the Wynn is its enormous rooms - perfect for having your whole group over for cocktails before heading out on the town.
Caesars Palace Hotel & Casino Rating: 4.0 Pearls
Balancing low-key partying with ample pampering, Caesars Palace is a great choice for bachelorettes. (Don't let that bachelor party gone awry in The Hangover dissuade you.) Qua Baths & Spa, one of the best spas in Vegas, offers, among other delights, its own Roman baths, Laconium steam baths, and Vichy showers; a day pass costs $45. The two-story Pure nightclub has four distinct spaces, each with its own DJ, so you can scope out the right crowd for your mood. And the adults-only Venus Pool is a bit more laid-back than some of the other, more notorious pool parties in Vegas.
Hard Rock Hotel & Casino Rating: 4.0 Pearls
Hard Rock is for ladies who are, well, ready to rock. By day, the Beach Club Pool is about the craziest scene on the Strip -- especially on Sunday, when it hosts the Rehab pool party. At night, the clubs Body English and Wasted Space -- both known to attract celebrities such as Paris Hilton and Kevin Federline -- are Vegas favorites. After-hours, you can scarf down some American fare at the 24-hour restaurant.